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As shown in Supplementary Fig. S2, the N-termini of the predicted mature sequences of all four identified MFG 110 proteins 1L, 2L, 4L, and 5L and also of pI329L were confirmed by MS. For 44 additional of the 94 identified proteins the N-terminal peptides were identified (Supplementary data, Table S1).
As mentioned above, we have identified 307 SNPs within the mature sequences of 171 miRNAs in rice.
Biochemical experiments showed that TDP-43 directly binds the mature sequences of a subset of the TDP-43 regulated miRNAs, including miR-423-3p miR-423-3p miR-423-3p
Cross-referencing raw data from a recent study using individual-nucleotide resolution cross-linking immunoprecipitation (iCLIP) approach (Tollervey et al., 2011), we found that TDP-43 might bind directly to the mature sequences of five miRNAs that were down-regulated after knockdown of TDP-43 in at least one of our cell lines.
The mature sequences of miR-433 and miR-127 were identical among the eight species.
Mature sequences of 3 split tRNAs (tRNAiMet, tRNALys and tRNAGln) branched with other tRNAs with same anticodon from Crenarchaeota and Euryarchaeota lineages.
Similar(9)
The mature sequence of miR-130a is conserved across various species including mammals, birds, amphibians and fish (Fig. S1).
The 5′ mature sequence of the 17S rRNA in these structures also appears to be in a mature conformation, but the leader sequence at the 5′ end is highly flexible (Fig. S3).
In this model, the 5′ mature sequence of the 17S rRNA would form a different secondary structure (h1′) other than that seen in the mature 16S form (h1) (Fig. 4E), with base paring between residues 7 to 16 and −1 to −10 of the leader sequence (Young and Steitz, 1978).
The mature sequence of this miRNA is agagaagaagaucagccugca.
The mature sequence of this miRNA is aaccagcaccccaacuuuggac.
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