Sentence examples for mature moDC from from inspiring English sources

Moreover, we found that mature moDC from patients produced significant higher levels of IL-12p40, TNFα and MIP-1α compared with mature moDC from healthy controls.

A significant difference (* P < 0.05 and ** P < 0.01) for the levels of six different cytokines was found when comparing mature moDC from pSS patients with mature moDC from healthy controls.

Expression of CCR7 is increased in mature moDC from pSS patients, which could lead to an increased homing ability of these cells.

We also analyzed the amounts of phosphorylated Stat1 levels, and detected significantly less p-Stat1 (S727) and reduced p-Stat1 (Y701) in mature moDC from pSS patients.

Decreased levels of Stat1 in mature moDC from pSS patients might thus cause higher RelB activation and eventually lead to elevated cytokine production.

We found significantly decreased levels of the chemokine of IL-7 and IFN gamma in mature moDC from pSS patients compared with controls.

IL-12p70 was secreted in small amounts by mature moDC, but washout secretedant dinferencesmallween moDC from pSS pamounts compared with controls (data not shown).

We compared unphosphorylated Stat1 and Stat3 as well as phosphorylated p-Stat1 (Y701), p-Stat1 (S727) and p-Stat3 (Y705) in protein lysates from immature and mature moDC.

As expected, Bim expression was increased in mature moDC, but the expression did not vary between moDC from patients and controls.

To obtain mature MoDC, TNF-α was added during the final three culture days.

While our data provide further support for previous studies that have indicated an impaired differentiation of immature towards mature MoDC, they also clearly demonstrate a qualitatively and quantitatively altered cytokine secretion at the level of immature MoDC, which may in part explain the reduced allostimulatory capacity of these cells.