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These methods could potentially distinguish children at different developmental stages of cognitive maturation, which may be relevant to establish whether psychopathologies suffer from a maturational delay, like attention deficit hyperactivity disorder (ADHD) [ 95] or from a deviance from normal development.
In other species, development of a colourless gametophyte is slow, so at maturation, which may require up to eight years, the fleshy gametophyte will have become buried in successive layers of humus.
HSV-2 infection alters the function and phenotype of monocytes [6] [8], impeding their maturation, which may in turn alter the phenotype and function of interacting CD4+ and CD8+ T cells.
Concomitant with faster sub-adult growth rate might be changes in timing of maturation, which may affect recruitment dynamics and productivity of the fish stocks.
In addition, genetic variants in miRNA genes may also have important roles by affecting miRNA maturation, which may affect disease susceptibility [ 8].
With longer differentiation time, astrocytes acquired multiple extended processes indicative of physical maturation, which may contribute to their regulation of BBB phenotype.
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Therefore maintenance of pluripotency in primordial germ cells while undergoing a defective maturation process, which may include premature activation of meiosis, could underpin the specification of these cells as CIS and tumorigenic.
Finally, many of the virulence associated functions and structures such as cell-wall lipids and LAM [ 103], that we have already identified as important for fitness in these DCs are known to be involved in preventing phagosomal maturation, properties which may in part explain the intra-DC fitness costs of mutating these genes.
Furthermore, TGFβinhibits recruitment of pericytes to the vasculature, thus decreasing vessel maturation and flow which may also negatively impact on tumour development [38].
Older girls had higher vaginal maturation index values, which may represent the effect of their own synthesis of estrogen.
HU also induces specific patterns of expression for homeostasis related genes and modulation of mRNAs and proteins for ECM deposition, maturation and remodeling which may be key factors for bone maintenance.
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