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Since mutations synthetic lethal with rps15-1 were identified in NHP2 and UTP15, two genes coding for proteins known to have a role in the early steps of pre-RNA maturation, we sought to characterize the rRNA sub-cellular distribution in the double mutant strains to understand the origin of the synthetic lethal relationship.
Because miR-155 is strongly induced in DCs upon maturation, we sought to determine whether its expression holds immunological significance.
Given the importance of TLR in driving APC maturation, we sought to quantify TLR transcript levels of B cell subsets.
To define the mechanisms by which Pak2 regulates thymocyte development and maturation, we sought to determine Pak2's function in TCR-induced signaling events.
Since we have recently demonstrated that LF blocks NF-κB translocation [ 9], and we have shown here that LF treatment inhibits DC maturation, we sought to assess whether LF-treated DC could induce tolerance to a nominal antigen such as KLH.
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Since extracellular matrix plays an essential role in heart development and maturation in vivo, we sought to develop a synthetic culture matrix that could enhance functional maturation of iPSC-CMs in vitro.
As IFNAR1 is important in DC maturation and function, we sought to first investigate the distribution of CD103+ and CD103− DC populations in steady state conditions.
Before examining the effects of Pen-2 mutations on complex assembly, maturation, and activity, we sought to identify the factors needed for rescue of the Pen-2 KO cells and detection of substrate cleavage activity.
We sought to characterize AVF maturation in a national sample of prevalent hemodialysis patients in the United States.
Noting the strong correlation between neuronal maturation, nucleolar snoRNA accumulation and paternal Snrpn Ube3a allele decondensation, we sought to further understand the link between transcription and chromatin decondensation for Snrpn Ube3a through genetic mutation.
We sought to enhance the viability and functional maturation of cardiac tissue constructs by cyclical stretch.
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maturation we deleted
maturation we determined
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maturation we used
maturation we characterized
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maturation we performed
maturation we asked
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maturation we stained
maturation we did
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maturation we observed
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