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Because mechanical loading increases during development and facilitates cardiac maturation, we hypothesized that afterload would promote maturation of EHTs.
Because BCOR is a known corepressor of BCL6, an important regulator of germinal center formation in B-cell maturation, we hypothesized that BcorNeo/Y and BcorGt/Y cell contribution to germinal center formation might be blocked or reduced in chimeras.
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Because fetal liver is an important hematopoietic organ for erythroid development, we hypothesized that hFLSCs might produce protein(s) that support in vitro terminal maturation of erythroid progenitors.
Moreover, regarding the key role of the neonatal period in GALT maturation, we also hypothesized that early modifications of intestinal ecology and physiology would impact intestinal sensitivity to inflammation later in life.
Further, given that individuals with ASD were supposed to have brain growth dysmaturation during early childhood, we hypothesized that the abnormal neurodevelopmental maturation should extend to span adolescence.
We hypothesized that sexual maturation, which coincides with a falling incidence of HUS, may induce a relatively Stx-resistant state in the renal cells.
We hypothesized that QIL1 promotes the maturation of the MICOS complex by acting as a scaffold at the IM, bridging a sub-complex containing MIC60, MIC19, and MIC25 to other subunits including MIC10, MIC26, and MIC27.
Because DC maturation and cytokine production are NF-κB dependent, we hypothesized that blocking NF-κB activity in DC by selectively targeting IKKβ with a specific NEMO binding domain (NBD) peptide could inhibit the maturation of DC and thereby modulate the immune response.
Therefore, we hypothesized that the absence of cumulus cells during maturation can affect the nuclear and molecular maturation of the resulting oocytes.
We hypothesized that both high uptake and maturation might be achieved by combining prolonged R848 incubation (24 h) followed by the addition of CC.
Therefore, we hypothesized that unknown growth proteins are produced as yet unidentified populations of fetal liver stromal cells that stimulate the maturation of erythroid progenitor cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com