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For mature cells, maturation was induced on day 5 by adding 100 ng/mL lipopolysaccharide (LPS, Sigma) or DH5α bacteria (Stratagene) and allowing maturation to proceed for 24 hours.
The cells were then either taken as immature CD34DCs or were matured by culturing them in the growth medium supplemented with either 100 ng/mL LPS (Sigma) or DH5α bacteria (Stratagene) and allowing maturation to proceed for 48 hours.
As soon as Id proteins are downregulated, the bHLH activity of these "primed" cells would be released from inhibition, allowing epiblast maturation to proceed.
Her argument's plausibility increased with the discovery that leptin permits sexual maturation to proceed by conveying a signal that fat stores are adequate for reproduction [ 17- 19].
As discussed earlier, our data that only a small number of target genes are significantly deregulated suggests that other aspects of the Zfp335-dependent transcriptional program may remain sufficiently intact to allow most developmental processes, except for T cell maturation, to proceed relatively normally.
Similar(55)
An alternative explanation of the observed sexual heterochrony could be that the observed expression differences are remnants of brain maturation rate differences that arise during adolescence, when female brain maturation is known to proceed slightly faster [reviewed in (Lenroot & Giedd, 2010)].
Oocytes injected with siRNA duplex oligonucleotides were maintained in prophase I for either two or five hours (referred to as siTPX2-2h and -5h, respectively), then meiotic maturation was allowed to proceed.
In order to maximize the efficiency of the depletion, in the light of TACC3 being already present in prophase, oocytes injected with the siTACC3 were maintained in prophase for a prolonged period of time (30 hours) before meiotic maturation was allowed to proceed.
Meiotic maturation was then allowed to proceed and spindle assembly was analyzed by time-lapse videomicroscopy, taking advantage of the association of YFP-TPX2 with spindle microtubules.
This could well be the result of inhibition of proliferation, a process required to proceed through the maturation process [ 50].
Tissue-specific gene repression is thought to proceed during the maturation of islet cells during postnatal stages (Thorrez et al., 2011), a period when β cells acquire a mature GSIS (Blum et al., 2012).
More suggestions(15)
ripening to proceed
maturation to prevent
maturation to accelerate
maturation to betamethasone-phosphate+betamethasone-acetate
maturation to represent
maturation to drive
maturation to determine
maturation to amino
maturation to allow
maturation to come
maturation to germline
maturation to develop
maturation to imago
maturation to reach
maturation to yield
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