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In the normal process of long bone development, chondrocyte hypertrophy is followed by hypertrophic chondrocyte maturation to allow the invasion of osteoblasts and blood vessels.
Gonads in half-worms had often undergone sufficient maturation to allow self-fertilization and progeny production.
The binding of such ligands also promoted the correct series of steps in terminal N-glycosylation and maturation to allow cell surface delivery of the mutant α1b-adrenoceptor.
Another possibility is that Smarca1 and other SWI/SNF factors might facilitate Foxa1/2 binding to different target sites in neurons at distinct phases of their maturation to allow for gene expression through promoting an open chromatin state at these targets.
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High levels of TOC require a long maturation phase to allow proper humification.
However, B cells are no different from other APC in their need for maturation signals to allow them to attain their full presentation capacity.
Additionally, cardiac overexpression of miR-195 results in pathological cardiac growth and heart failure in transgenic mice [53], so that modulation of miR-15 miRNAs during development and maturation are unlikely to allow specific conclusions about the effect of miR-15 miRNAs on elastin metabolism.
Furthermore, during alveolar stage, the lung vasculature, which still consists of a double layer of capillaries, becomes a single capillary network via a process called microvascular maturation in order to allow more efficient oxygen intake (Fig. 1d).
Together, these data suggest that maintenance of the neuromuscular synapse is governed through its lateral association with the muscle cytoskeleton, and that dystrophin has a direct role in promoting the maturation of synaptic folds to allow more sodium channels into the junction.
But as with any wound, after the insult has been removed, a proliferation period is needed to rebuild what was broken and a maturation period is required to allow remodeling to take place.
Lysates were then incubated overnight at 37°C to allow maturation (7).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com