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The TNF-producing cells were more mature, again suggesting that the changes in the maturation state of donor thymocytes correlated with increasing capability to produce TNF efficiently on a per cell basis.
The greater increase in primary astrocyte cultures compared with the astrocytes present in the OPC cultures could also be due to differences in the maturation state of astrocytes, suggesting that only more mature cells can highly express noggin.
Moreover, the maturation state of murine dendritic cells previously incubated with either Pam2CGalp or Pam2CGalf was monitored by flow cytometry and compared to that induced by lipopolysaccharide.
A comparison of the relative extents of PCNA- (proliferative), nrd- (freshly determined) and Hu-positive (differentiating) cell populations allows to determine the relative maturation state of a given brain part.
Finally, we showed that integration to cartilage in-vitro is not correlated to the maturation state of TE constructs, but rather their maturation rate, providing a proof-of-concept for the use of TB-TE to enhance treatment outcomes following cartilage injury.
We next assessed the effect of infection with MVA and MVA-B on the maturation state of MDDC.
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A pediatrician assessed pubertal stage according to a two-point scale as 1) pre-pubertal stage (including Tanner stage 1) and 2) ongoing maturation or mature state of development (including Tanner stage 2, 3, 4 and 5).
Interestingly, different maturation states of the E proteins of DEN sE (P) during the viral life cycle are characterized by a different DI + DIII relative to DII angle (Zhang et al., 2004).
The Th1 or Th2 responses elicited by APCs may be influenced by many factors, such as the maturation states of the APCs and routes of antigen uptake.
Collectively, these sections span the growth and maturation states of the stem, and they also represent a cell wall development continuum.
In regards to the relationship between the maturation states of a monocytic cell to their polarization propensity, an earlier study had indicated that immature macrophages secrete more IL-12 [ 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com