Sentence examples for maturation phenotype of from inspiring English sources

Taken together, these data suggest that maturation phenotype of a given T cell response is not predictable by the restricting HLA type or by the epitope specificity.

This phenomenon is also consistent with the activation and maturation phenotype of B cells, which display decreased expression of CD21 [47].

Given these results with unstimulated bulk CD8+ T cells, we next investigated the maturation phenotype of the HIV-1-specific fraction of CD8+ T cells.

We investigated the maturation phenotype of epitope-specific CD8+ T cell responses directed against HIV-1 in 42 chronically infected, untreated individuals, 22 of whom were "Controllers" (median 1140 RNA copies/ml plasma, range<50 to 2520), and 20 "progressors" of whom had advanced disease and high viral loads (median 135,500 RNA copies/ml plasma, range 12100 to >750000).

The maturation phenotype of MoDC in the presence of LPS + IFN-γ was assessed.

Other studies, demonstrated that ZA modulates the differentiation, maturation, and functions of DCs, indicating that ZA may act at the differentiation stage of DCs to suppress the generation and maturation phenotype of DCs.

Germination- and loss of the hydrophobin layer- results in exposure of β-glucan, a ligand for dectin-1, resulting in stimulation of inflammatory cytokines from macrophages and activation of specific maturation phenotypes on dendritic cells (DC) [1] [5].

In contrast, NK cells from a young origin developing in an aged environment acquired a maturation phenotype reminiscent of that of aged donor NK cells (baseline) in both the spleen and BM (Fig. 3B and C and data not shown) 2 weeks postchimerism.

The donor CD45.1+ SP P14-CD8+ thymocapableapable of TNF production also exhibited an increasing maturation phenotype (down-regulation of CD24 and up-regulation of CD45RB and Qa2) that approached a level similar to that of splenic T cells by day 14 after transfer.

Maturation phenotype was independent of the HLA restriction or the specificity of a given CD8+ T cell response and individual epitopes associated with slow disease progression were not more likely to be terminally differentiated.

Co-depletion of both WEE-1.3 and CDK-7 suppressed the precocious oocyte maturation phenotype exhibited by depletion of WEE-1.3 alone and returned the gonad to a more wild-type expression pattern, with the three to four most proximal oocytes being pH3-positive and Nop1p-negative.