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We investigated phenotypical maturation pattern of lymphocytes in ASCT recipients and in HIV patients, analyzing cells based on the expression of CD45 isoforms and chemokine receptor CCR7.
A population PK model-based approach allowed estimation of individual apparent clearances to explore the maturation pattern of sirolimus clearance.
Gene mutations and other factors that disturb the normal maturation pattern of chondrocytes generally result in chondrodysplasias and other forms of dwarfism and skeletal deformities [ 4].
In another study on ontogeny in preterms performed by means of EGG and ultrasonography, a clear maturation pattern of gastric motility was shown [ 126].
To identify how physicochemical drug properties influence the maturation pattern of UGT2B7-mediated glucuronidation, in vivo clearance values of hypothetical UGT2B7-specific substrates with physicochemical properties that are common for small-molecular drugs were simulated with Simcyp.
To define preconditions for the use of this semiphysiological function, the influence of system- and drug-specific parameters on the net maturation pattern of in vivo UGT2B7-mediated glucuronidation was investigated.
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The different vulnerability of DA fibres in distinct areas might be related to varying maturation patterns of the DA fibres.
Here, we assess the maturation patterns of coastal Atlantic cod (Gadus morhua) in Skagerrak, where studies using neutral markers have revealed genetically differentiated populations of this harvested fish within tens of kilometres of coastline.
We have also used these native colonic tissues to further look at maturation pattern and localization of wt- and mutant-CFTR protein, which can serve as a valuable tool to evaluate the effects of CFTR-modulators together with Ussing chamber measurements of CFTR-mediated Cl- secretion.
This maturation pattern may represent enhancement of efficiency of information flow between network components, which has been suggested in human brain maturation (Fair et al., 2007; Stevens et al., 2009).
Several hypotheses have been proposed to explain the non-random maturation pattern and high levels of seed abortion observed in most plant species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com