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Finally, when tested in an ectopic model in rabbit, the scaffold produced a large volume of trabecular bone in only two weeks, that subsequently underwent maturation over time as expected, with increased mature cortical bone formation, supporting its ability to promote bone regeneration in clinically-relevant scenarios.
Twelve papers examined outcome regarding (a) graft maturation over time and (b) graft integration in the bone tunnels.
In Figure 7, fluorescence optical microscopy visualization of YFP-paxillin REF52 shows cell spreading and FA maturation over time.
This may be due to difficulties in testing very young children or due to the fact that effect of pollutants may become apparent only with maturation over time.
Additionally, significantly more fiber outgrowths were seen at the six-week time point, demonstrating a progressive neuronal maturation over time of the grafted HNPC.
Furthermore, we found O4+ oligodendrocyte precursor cells in the migration area that increase in number and degree of morphologic maturation over time (Baumann and Pham-Dinh 2001).
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For example, retest reliability can be influenced by developmental maturation over the time interval, or training by the caregiver following mistakes seen in the first assessment.
Above all, the Study reveals how men like Dr. Camille adapted themselves to life and adapted their lives to themselves a process of maturation that unfolds over time.
Moreover the effects of different co-culture environments on Mk differentiation and maturation were examined over time.
A further development of the BrdUrd comet assay is the introduction of a pulse-chase step, to allow the maturation of DNA over time (McGlynn et al, 1999).
The addition of a control group allows us to control for the natural maturation of participants over time and for selection effects.
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