Sentence examples for maturation or trafficking from inspiring English sources
Although the mutation is located at the distal C-terminus, it does not undergo normal channel maturation or trafficking to the plasma membrane.
However, inhibition of this appeared to affect maturation or trafficking of PfSUB1 and other secreted parasite proteins, so this may have been an indirect effect on PfSUB1 expression.
It is conceivable that a number of other mechanisms could also, perhaps to a lesser extent, contribute to the temperature effect on hERG expression, such as an improvement in protein folding, maturation or trafficking to the cell surface.
Therefore, it is plausible that the use of chemical inhibitors to block or neutralize acidic host-compartments inhibits processes involved in CAMP maturation or trafficking, thereby preventing activation of PhoQ.
Alternatively, a decrease in the number of B cells, a change in the kinetics of plasmablast production, maturation or traffic, or a decrease in disease activity could all contribute.
First, normal surface localization was observed for R878C and G1408R, suggesting that these mutations affected channel gating or permeation properties rather than intracellular channel maturation and trafficking.
By drawing the endosomal system's architecture, RNF26 orchestrates endosomal maturation and trafficking of cargoes, including signaling receptors, in space and time.
Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone responsible for the activation, maturation, and trafficking of several hundred client proteins in the cell.
While it regulates maturation and trafficking of the complex, on the cell surface, short protein fragments present in blood or lymph could utilize this mechanism to alter the ligand composition on antigen presenting cells in a catalytic way.
In the present report we claim an essential and novel role for CypB in the maturation and trafficking of Na/Kα1-ATPase pump through the secretory pathway.
These data indicate that CypB through its interaction with Na/K-β1 might regulate maturation and trafficking of the pump through the secretory pathway.
