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This system, called cytoplasmic male sterility, or cytosterility, prevents normal maturation or function of the male sex organs (stamens) and results in defective pollen or none at all.
The T2D susceptibility genes identified so far are mainly involved in pancreatic β-cell maturation or function.
We hypothesized that PLCγ2 might regulate T cell activation by affecting DC maturation or function.
Altered premelanocyte migration, maturation or function is likely to be part of the mechanism for deafness in this breed, given the association between coat colour and markings and deafness.
The observed deficit in MNCV and SNCV in Ins2Akita/+ mice does not seem to reflect a delay of PNS maturation since we could not detect any differences in either myelin thickness or axonal size in three month old affected animals and our microarray data does not reveal any changes in the expression of genes involved in either Schwann cell or neuronal maturation or function (see discussion below).
It is unknown what role this glycosylation site might play in receptor maturation or function.
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Hence it is believed that restoring mutated channel maturation and or function will improve patient health [ 3].
Employing a new monoclonal anti-CIP4 antibody generated in our laboratory, we initially observed that the PCH family member CIP4 is expressed in T cells only after activation indicating a specific role in T cell maturation or effector function.
We demonstrate that while lack of IL-7 or IL-15 alone has minimal impact on splenic CD8+ T cell maturation or effector function development during acute Toxoplasmosis, absence of both IL-7 and IL-15 only in the context of infection severely down-regulates the development of a potent CD8+ T cell response.
To discriminate between a maturation or stabilization function of Yae1 or Lto1 for Rli1's Fe-S clusters, we established a method which allowed us to rapidly degrade Yae1 or Lto1 and then follow the fate of Rli1's Fe-S clusters.
Thus, defective SC maturation, function, or development causes disorders in spermatogenesis (reviewed in Sharpe et al).
More suggestions(15)
maturation or remodelling
maturation or platelet
maturation or reproduction
maturation or regulation
maturation or mobility
maturation or ejection
maturation or degeneration
maturation or survival
maturation or development
maturation or degradation
maturation or differentiation
maturation or stem
maturation or homeostasis
maturation or blockage
maturation or stability
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