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To test this hypothesis, we employed a co-culture system designed to facilitate the maturation of progenitor cells to either B or T lymphocytes.
WASP is also believed to contribute to maturation of progenitor T and B lymphoid cells.
PrPC N-glycosylation differences have been linked to maturation of progenitor 1C11 neuronal cells to serotonergic or nor-adrenergic neurons.
Furthermore, the advent of stem cell research has underscored the importance of extracellular cues for the efficient differentiation and maturation of progenitor cells.
Taken together, these findings indicated that COUP-TFII itself is indispensable for the Leydig cell differentiation process, particularly related to the step involved in maturation of progenitor Leydig cells to adult Leydig cells.
To this end, we used a loss-of-function approach, analyzing in mice ablated of PC3/Tis21 the maturation of progenitor cells of the dentate gyrus, in the adult hippocampus (P60), or in the developing hippocampus (at P14), when the population of differentiating new progenitor cells is massive [45].
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This peptide, Peptide 6, induced proliferation and increased survival and maturation of neural progenitor cells into neurons in the dentate gyrus of normal adult C57BL6 mice.
Therefore in models of prenatal cocaine exposure both migration and maturation of these progenitor cells is delayed.
Olig1 is critical for the maturation of oligodendrocyte progenitor cells (OPC), and Olig1 immunostaining becomes progressively more cytoplasmic during OPC maturation.
The results of this study show the potential of decellularized, solubilized extracellular matrix coatings derived from muscle to promote maturation of committed progenitor and stem cells in vitro, demonstrating this method's applicability to muscle cell culture; however, the general technology has wide ranging implications.
Erythropoietin cells express calcitriol receptors, which induces proliferation and maturation of erythroid progenitor cells.
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