Sentence examples for maturation of multiple from inspiring English sources

Developing novel biomarkers indicative of the maturation of multiple organ systems can improve upon our current methods of fetal maturity testing which focus solely on the lung, and will better inform obstetrical decisions regarding delivery timing.

The critical role of the PCs in the proteolytic maturation of multiple precursor substrates implicated in neoplasia makes these enzymes attractive targets in cancer therapy [39].

It should be noted that in mice maturation of multiple oocytes in one cycle is natural, while in humans it is not.

Transcription factors of the bHLH family direct the proliferation, specification and maturation of multiple neuronal lineages (Atchley and Fitch, 1997; Guillemot, 1999; Ross et al., 2003).

While the present sample size is small, the data identify biologically plausible candidate genes relevant to the maturation of multiple organ systems.

We found that Lsd1 represses genes that are normally expressed in hematopoietic stem and progenitor cells (HSPCs) and that failure to silence HSPC gene signatures during differentiation is incompatible with terminal maturation of multiple blood lineages resulting in severe pancytopenia.

HSP90 is a chaperone essential for maturation and stabilization of multiple client proteins.

Post-transcriptional processing, including maturation of primary tRNA, multiple chemical residue modifications, and aminoacylation, are critical to accurate and effective translation.

Cardiac morphogenesis and maturation require the deployment of multiple cell lineages that are derived from the primary heart field, secondary heart field, and neural crest cells [4 6].

1 Synthetic immunostimulatory oligonucleotides such as double-stranded RNA or unmethylated cytosine guanosine motifs (CpG-ODNs) mimic molecular signatures of pathogens (viruses or bacteria, respectively) and trigger an immunostimulatory cascade including maturation, differentiation and proliferation of multiple host immune cells through pattern recognition receptors.

Overall, our results not only provide structural insights into the in vivo maturation of the 30S subunit, particularly at both early and late stages of the 3′ domain assembly, but also demonstrate the presence of multiple rRNA maturation checkpoints along the assembly pathway.