Sentence examples for maturation of inflammatory from inspiring English sources

CASP1, CASP4, CASP5 and CASP12 belong to a caspase subfamily called the inflammatory caspases, which are involved in the maturation of inflammatory cytokines (Il-1β and IL-18) in addition to their role in apoptotic pathways [9], [38], [39].

Inflammasomes can activate under autophagy-deficient conditions and promote maturation of inflammatory cytokines including IL-1β and IL-18 [ 85].

Autophagy-deficiency activates the inflammasome, which promotes the maturation of inflammatory cytokines, such as IL-1β and IL-18 [ 48].

Here, caspases represent key targets for drug development as they are central in initiation and execution of cell death and in maturation of inflammatory cytokines.

This suggests an important role of IL10 either in controlling the maturation of inflammatory monocytes in Mikulicz cells or the establishment of a proper environment for their occurence.

Furthermore, the recently discovered T-helper-17 proinflammatory cytokines, present in syno-vium samples, are associated with the migration, differentiation and maturation of inflammatory cells, and they facilitate a network of interactions between all components of the immune response.

The inflammasome promotes the maturation of the inflammatory cytokines Interleukin 1 β (IL-1 β) and Interleukin 18 (IL-18).

The proliferation of fibroblasts is directly related to the presence of macrophages in the healing process, as these release growth factors and cytokines essential for the maturation of the inflammatory phase and the beginning of the healing.

The caspases are a family of cysteine proteases important not only in starting and executing apoptosis, but also in processing and maturation of the inflammatory cytokines IL-1b and IL-18 [ 27].

The major characteristic of pyroptosis compared with other pathways of regulated necrosis is the maturation of pro-inflammatory cytokines such as IL-1 β and IL-18 during the cell death process.

The first, including the initiator caspases (caspase-2, -8, -9 and -10) and the effector caspases (caspase-3, -6 and -7), lead directly to apoptosis [ 6], while the others, including caspase-1, -4 and -5, are involved in the maturation of pro-inflammatory cytokines [ 7].