Sentence examples for maturation of granulation from inspiring English sources

Opioid peptides have already been used in animal models in treatment of wounds; they induce fibroblast proliferation and growth of capillaries, and accelerate the maturation of granulation tissue and the epithelization of the defect.

The formation and maturation of granulation tissue is a highly active process.

Diabetes can hinder the normal wound healing process by inducing long-term inflammation which can lead to delayed maturation of granulation tissues, reduced wound parallel tension and inhibition of angiogenesis [ 1].

It has been suggested that high-pressure gradients through the articular cartilage surrounding a defect could significantly impair chondrocyte production, matrix production, and maturation of granulation tissue at the defect site [ 8].

The faster wound contraction by BME may be due to stimulation of interleukin-8, an inflammatory α-chemokine which affects the function and recruitment of various inflammatory cells, fibroblasts and keratinocytes, and may increase the gap junctional intracellular communication in fibroblasts, and induces a more rapid maturation of granulation tissue [ 31].

These cells exhibit contractile properties, due to the expression of α-SM actin in microfilament bundles or stress fibers, playing a major role in the contraction and maturation of the granulation tissue.

Clinical and experimental data indicate that traditional NSAIDs delay the healing of gastroduodenal ulcers by interfering with the action of growth factors that restricts epithelial cell proliferation, maturation of the granulation tissue and impede angiogenesis [ 32].

These cells also exhibit contractile properties, due to the expression of α-smooth muscle actin in microfilament bundles or stress fibers, playing a major role in the contraction and in maturation of the granulation tissue [ 4].

According to morphological changes in the course of the healing process, these phases are described as an inflammatory phase, a proliferative phase for the development of granulation tissue, and a regeneration phase for maturation, scar formation and re-epithelialisation [ 3].

Wounds were histologically assessed for the presence of and dissemination of bacteria, host immune response, indications of wound healing, i.e., extent of epithelial migration, coverage, maturation, and amount of granulation tissue present within the wound, and if the wound and associated inflammation extended into the underlying vertebrae, spinal canal, and/or spinal cord.

Histological examination of wound tissues on days 4, 14, 18 and 21 after surgery demonstrated that this improvement was supported by enhanced growth, maturation and fibrous transformation of granulation tissue and earlier epithelization of the injured area in rats treated with DNIC-Col composites benchmarked against Col and SpWH.