Sentence examples for maturation of epidermal from inspiring English sources
Actually, the maturation of epidermal ICs is a very complicated process that involves sequential activation of many genes involved in cell differentiation, ion transport, acid-base regulation, as well as cell shape remodeling [4].
The keratin, type II cytoskeletal 2 oral, is synthesized during maturation of epidermal keratinocytes.
Our data demonstrate that melanoma cells inhibit the earliest steps of LC differentiation, but failed to affect the functional maturation of epidermal LC.
Our results demonstrate that the frequency and maturation of epidermal LCs were reduced in a stepwise fashion in aged mice, starting at 12 months old.
In the future, it will be important to understand how the egr-5 gene controls the proper differentiation and maturation of epidermal cells and whether these mechanisms are conserved in other animals.
However, egr-5, which is required for the stable maturation of epidermal progenitors and their progeny, does not appear to be required for the maintenance of the differentiated state.
Here, we investigate the effect of two melanoma clones differing in their invasive and metastatic properties on the generation and/or functional maturation of human epidermal LC.
Histologically, the skin shows hyperkeratosis, delayed maturation of skin appendages, epidermal thickening, abnormal collagen fiber morphology, and absence of elastin fibers (Holbrook et al., 1987; Dean et al., 1993).
It examines the various stains and biomarkers used to quantify processes such as angiogenesis, reestablishment of epidermal maturation, basement membrane integrity, and the establishment of nonepidermal cells in the epidermis.
Therefore, unveiling the downstream targets of egr-5 will help discern these possibilities, as well as provide more mechanistic insight on the role of egr-5 and the progression of epidermal fate maturation.
It is characterized by an abnormal cycle of epidermal development, with epidermal hyperproliferation, altered maturation of skin cells, vascular changes, and marked inflammation.
