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While there is evidence [4] [6] that microRNA expression and maturation is induced by signaling pathways, microRNAs also emerge as regulators of signaling proteins.
Other groups have reported that mature moDCs are harder to transduce than immature moDCs [21], [33], but to the best of our knowledge there has been no previous documentation of decreased transgene expression when maturation is induced after transduction.
DC maturation is induced using MCM, TNFα and PGE2.
These results suggest that the phagosomal maturation is induced by BCG-dHCM infection and is closely associated with the activation of naïve CD4+ T cells.
On one hand, a number of pro-inflammatory cytokines are produced (TNF-α, IL-12 and IL-1) and DC maturation is induced by the mycobacteria.
Human monocyte-derived DC maturation is induced by oxLDL exposure and this effect is mediated by lysophosphatidyl choline through the activation of a G-protein-coupled receptor (Coutant et al, 2002).
Similar(49)
For mature cells, maturation was induced on day 5 by adding 100 ng/mL lipopolysaccharide (LPS, Sigma) or DH5α bacteria (Stratagene) and allowing maturation to proceed for 24 hours.
In order to obtain follicle-enclosed oocytes in metaphase II of meiosis (C2 follicles) from the same females, gonadotropin-induced maturation was induced in vitro by further incubating immature stage VI follicles for 15 h at room temperature in OR2 buffer supplemented with 40 IU/mL of human chorionic gonadotropin (hCG; Organon, Puteaux, France).
SMC maturation was induced using a MEK inhibitor.
Lung maturation was induced in all treated cases, and all children were released in healthy condition.
Finally, we found that neuronal maturation was induced only during the first phase.
More suggestions(15)
growth is induced
processing is induced
ripening is induced
maturation is advanced
maturation is estimated
maturation is mediated
maturation is blocked
maturation is limited
maturation is delayed
maturation is thought
maturation is required
maturation is impaired
maturation is confirmed
maturation is shown
maturation is associated
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