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The mechanism(s) by which these areas are most sensitive to disruption is not obvious, but it is notable that these areas are known to mature relatively early in comparison with other cortical areas, with a gradation of maturation in which cortex closer to the insula matures earlier than cortex further from the insula.
This change was shown to occur during thymocyte maturation, in which PNA-positive cortex cells mature into PNA-negative medulla thymocytes.
Nudaurelia capensis omega virus (NωV) is a T = 4 icosahedral virus that undergoes a dramatic maturation in which the 490-Å spherical procapsid condenses to a 400-Å icosahedral-shaped capsid with associated specific auto-proteolysis and stabilization.
Nevertheless, our results help to build a model of experience-dependent somatosensory maturation in which isolated limb movements contribute to the mapping of somatomotor cortex over the equivalent of the last eleven weeks of gestation, and underline the importance of protecting active sleep in newborns48,49,50,51.
There's a particular period of maturation in which, with external stimulation of the appropriate kind, the capacity will pretty suddenly develop and mature.
Lysosome associated membrane proteins 1 and 2 (LAMP 1/2) are involved in phagosome maturation in which lysosomes fuse with late phagosomes leading to removal of endocytosed microbes [19].
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Furthermore, similar to growth plate development in which hypertrophic maturation is under the regulation of a feedback loop involving Indian hedgehog and parathyroid hormone-related protein (PTHrP) [ 35], PTHrP also plays a regulatory role in MSC terminal differentiation.
To further demonstrate the impact of Wnt signaling on erythroid maturation, we used an ex vivo erythroid maturation assay35,36 in which both FL -and adult BM-derived CD71+Ter119-/lo pre-erythroblasts are exposed to differentiation signals, including Epo, and allowed to mature to CD71+Ter119+ erythroblasts over 2 days (Fig. 5a, Supplementary Figure S6a).
To estimate the plasticity in age and size at maturation that stemmed from growth variation among the selection lines, we conducted a maturation experiment in which F8-generation fish (i.e. second generation after the selection was halted) were reared under three different feeding conditions (1%, 2%, and 4% of body weight in dry food daily) following the protocol in Uusi-Heikkilä et al.
In addition, the Progesterone-mediated oocyte maturation pathway, in which the target genes of oar-miR-200a-3p oar-miR-200a-3p oar-miR-200a-3p oar-miR-200a-3p oocyte [ 36].
After autophagosomes are formed, they undergo a stepwise maturation process in which they engulf organelles, fuse with lysosomes, and mature into autolysosomes with lysosomal enzymes [ 16].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com