Sentence examples for maturation in aged from inspiring English sources

However, a lack of IL-15 does not appear to be responsible for the impaired maturation of NK cells in aging as administering the IL-15/IL-15Rα IL-15/IL-15Rα IL-15/IL-15Rαment BM NK complexturatinn in aged mice.

To evaluate the effects of resveratrol on oocyte maturation in aged mice and humans.

Impaired NK cell maturation in aged mice correlated with a reduced capacity to eliminate allogeneic and B16 tumor targets in vivo.

However, whether defective NK cell maturation in aging influences their functional competence remains poorly understood.

If IL-15 was the limiting factor in aging, then administering IL-15 would compensate for this deficiency and augment NK cell maturation in aging.

Additionally, we included a control group of participants to investigate whether maturation in age had an effect by itself on moral reasoning in this age group.

This meant that any potential differences or changes in DIT scores could be attributed to the education process rather than to students' maturation in age.

Consistent with impaired aged NK cell maturation, expression of T-bet and Eomes, which regulate NK cell functional maturation, was significantly decreased in aged bone marrow (BM) NK cells.

Therefore, while the aged nonhematopoietic environment may impair NK cell maturation, other factors including defects in the hematopoietic environment as well as intrinsic defects in hematopoietic stem cells (HSCs) and NK cell precursors may also contribute to the impaired NK cell maturation and function in aging.

Interestingly, the presence of young BM cells in the BM inoculum did not augment aged NK cell maturation in sublethally irradiated aged recipients and nor did the presence of aged BM cells impair the maturation of young NK cells in sublethally irradiated young recipients.

We evaluated whether extrinsic or intrinsic factors were responsible for the impaired maturation and function of NK cells in aging and whether impaired maturation correlated with functional hyporesponsiveness.