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However, the discovery that microbial products activate host cells via pattern recognition receptors such as Toll-like receptors (TLRs) and enhance adaptive immune responses by triggering cytokine production and dendritic cell maturation, has led to TLR agonists being developed as vaccine adjuvants [14] [18].
The vital supporting role of cumulus cells during in vivo and in vitro maturation has led many groups recently to focus research interest on cumulus cells.
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Yet, the maturation of female candidates has led some women with high-profile track records to take on or at least consider major challenges: Geraldine A. Ferraro hopes to unseat Senator Alfonse M. D'Amato in New York, and Senator Dianne Feinstein is considering a race for governor in California.
The importance of assessing bone maturation levels in our patients (so as to be able to emit a proper diagnosis and design suitable orthodontic planning) has led us to study different bone maturation indicators.
Despite the conflicting information given by a handful of early published studies where both concordance[7] [9] and discordance[10] [12] between technologies was demonstrated, the maturation of microarray technology and data analysis methods has led to improved cross-platform correlations[6], [13].
There is evidence that incidental artificial selection caused by heavy fishing has led to a compensatory growth response, i.e. faster growth and earlier maturation.
The remarkably early development of the zebrafish circadian clock in the pineal gland has provided a unique opportunity for a thorough investigation of this timing system and has led to the discovery of mechanisms that underlie its maturation.
After Drake's maturation process from Comeback Season to his current role as Young Money's prized possession has led him to create a label that stands alone and rightfully so.
And since 2001, Bane has led the company to expand to 474 at the time of the podcast recording by formalizing the strategy and focusing the business a period of maturation.
Current limitations in computational design methodology have led to the adoption of high-throughput screening and affinity maturation techniques to diagnose modeling inaccuracies and generate high activity binders.
have led to convictions.
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