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Through the application of these fluorescence based methods it is now widely accepted that the formation of homo- and/or heterodimers or higher order complexes is a universal aspect of GPCR biology [ 193] and could have important functional roles, e.g. in receptor maturation, function and trafficking [ 194, 195].
We investigated the role of NK-DC cross-talk on maturation, function, and susceptibility to viral replication of HIV-1-infected iDCs.
Recent studies have shown that miRNAs can control maturation, function, and maintenance of dendritic cells [ 3- 5].
Osteocytes are linked metabolically and electrically through gap junctions composed primarily of connexin 43, which are required for osteocyte maturation, function, and survival [ 18].
However, tumours have the capacity to limit APC maturation, function, and infiltration of the tumour site (Gabrilovich et al, 1996, 1997, 1998; Qin et al, 1997).
As a basis to address unsolved issues regarding the maturation, function and cell type-specific composition of the cytotoxic effector compartment in T cell populations, we now analyzed the proteome of enriched secretory lysosomes from in vitro activated human T cell blasts.
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During this time, enormous growth of the fetus, maturation of function and cell types in every organ, and acquisition of individual attributes occur.
The last cytokine specifically produced by DP T cells, IL-5, is generally regarded as a Th2 cytokine involved in eosinophil maturation and function and in B cell growth and antibody production.
While the role of ACE (CD143) on circulating monocytes remains unknown, the renin-angiotensin system is critical for monocyte maturation and function and targeting this signaling axis may be of therapeutic benefit in monocyte-driven human disease [98,99].
We also found that Dp71 loss affects synaptic maturation and function, and results in deficits in selective cognitive functions.
Mural cells exert a dominant effect on endothelial cell behavior that is necessary for vessel maturation and function, and that determines responses to anti-angiogenic therapeutics [2], [3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com