The early success of bevacizumab in the metastatic setting led to the development of ECOG-5103, which tested a standard backbone of chemotherapy with concurrent or concurrent plus sequential bevacizumab in the adjuvant setting with results pending maturation of efficacy data.
This result indicates that efficacy of maturation is cell type dependent.
Studies in mice also suggest that it would be crucial to deliver the normal gene before maturation of the photoreceptors for maximum efficacy of treatment rather than delivering the gene after maturation (Byrne et al., 2014).
To evaluate the feasibility and the efficacy of in vitro maturation (IVM) when immature oocyte collection was performed in the early follicular, late follicular, or luteal phases in women with cancer who require urgent chemotherapy.
To investigate the efficacy of in vitro oocyte maturation (IVM) in women with repeated failure of IVF treatments due to follicular developmental abnormalities.
These results further strongly substantiate the efficacy of A. squamosain collagen maturation during wound repair.
The purpose of this study was to compare efficacy on fetal lung maturation of intra-amniotic betamethasone or budesonide with the efficacy of maternal intramuscular betamethasone.
The efficacy of antenatal steroids for fetal lung maturation in the periviable period is not fully understood.
Even with evidence showing a role for PPARs in oligodendrocyte regulation, conflicting data regarding the efficacy of these agonists on promoting OPC maturation or differentiation have been documented.
The binding of Ras to PI3K is specifically involved in clathrin-independent endocytosis, endosomal maturation, and intracellular transport of viruses, which result in decreased infectious efficacy of different subtypes of influenza viruses in cells lacking the Ras PI3K interaction.
