Sentence examples for maturation by the from inspiring English sources

However, targeting antigen delivery to DEC205+ DCs alone is insufficient to fully mature DCs and thereby stimulate an immune response; DC maturation by the co-administration of agents such as polyinosinic:polycytidylic acid (poly I C) with the DEC205 antibody-antigen fusion drives enhanced CD4+ T-cell vaccine-driven responses [ 13].

Interestingly, and in contrast to the effect of HBD as part of TSP-1, no inhibition of DC maturation by the rHBD was documented in our system.

These consist in the tight regulation of the polypeptide chain maturation by the quality control system in which N-glycans play a central role during the entire process.

In the observed higher migration capacity of MVA-B-infected MDDC, we think that the expression of HIV proteins could have a role in accelerating apoptosis and inducing a lower proinflammatory chemokine expression (as demonstrated in this study), which would allow a slightly higher degree of maturation by the added maturation cocktail.

Similarly, inhibition of Big ET-1 maturation by the furin convertase inhibitor abrogated MMP-2 synthesis.

Previous examples of processing in Pyrococcus were limited to tRNA processing by RNase P [ 47] and crRNA maturation by the Cas 6 endonuclease [ 42, 48].

Furthermore, TGFβ1, a member of the TGFβ family, promoted CGN maturation by increasing the expression of Kv2.1, the main α-subunit of the IK channel, via a non-Smad pathway [ 12].

Because SD could decrease M.tb replication in macrophages, we next investigated the involvement of SD in phagosomal maturation by studying the co-localization of the FITC-labelled M.tb strain H37Ra with LysoTracker Red.

HIV protease inhibitors, restrain the viral maturation by preventing the formation of structural and functional proteins and form immature, non-infectious virus.

Castanospermin inhibits alpha-glucosidase, an enzyme that plays a critical role in viral maturation by initiating the processing of the N-linked oligosaccharides of viral envelope glycoproteins.

To study the mechanisms by which cumulus cells (CCs) promote oocyte maturation by observing the effect of removing the cumulus oophorus on nuclear and cytoplasmic events during in vitro maturation.