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Similar to the development and validation of model-based approaches in the field of maturation based on system specific information [ 27, 28], the quantitative functions described can be used to quantify the impact of pregnancy or oral contraceptives on phenotypic UGT1A1 or UGT1A6 glucuronidation.
d, Longitudinal development of the microbiome maturation based on the microbiota age and MAZ score against the age of the infant at sampling (n = 11,717).
Wasserman, R. et al. A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly.
Selected individuals were examined for sexual maturation, based on the presence of releasable sperm from the males or the presence of vitellogenic oocytes in the females.
Altogether, the above results show that ABGCs form two functionally distinct populations during a long period of their maturation based on their different sensitivity to temporally organized inputs.
The E. coli ortholog of TTHA1045, YbeY, may be involved with rRNA maturation based on mutagenic studies and its strong genetic interactions with PNPase and RNase R [ 28].
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For user, defined number of times, the B-Cell is shown to the antigens from all groups and fitness value is calculated; population pruning is done after that, two affinity maturations based on cloning and mutations are performed and some random selected antigens from the same group are inserted to the set.
This lends support to the theory that the cam deformity may evolve during the dynamic period of physeal maturation and prior to skeletal maturity, based on significantly increased alpha angles seen post physeal closure, specifically in males.
Similarly, maturation schedules (based on age-specific proportion of mature females) also varied based on size-limit and fishing mortality rate.
Therefore, we adjusted the sampling schedule to one Daphnia generation by calculating maturation time based on the surface water temperature [ 39] and experimental data [ 37].
At 4 weeks of age, miR-29a mutant TECs showed a normal maturation profile (based on CD80 surface marker staining), and the relative numbers of mature and immature mTECs were comparable with those of their WT littermates (Fig. 4A).
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