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The maturation process is modeled via a deterministic maturation reaction norm (MRN) approach (i.e., a fish would mature if its length is above the threshold for maturation at a given age; Stearns and Koella 1986; Heino et al. 2002).
The timing of these defects is noteworthy given that many other gametophytic mutations (the pollen development defective class of mutants; pdd) disrupt pollen maturation at a stage prior to germination [12].
Mammalian Notch receptors (Figure 1A) normally undergo proteolytic processing by a furin-like protease during maturation at a site termed S1 that lies about 70 amino acids external to the transmembrane segment [2], yielding two non-covalently associated extracellular (NEC) and transmembrane (NTM) subunits [2], [3], [4].
Our results suggest that physiological state prior to the spawning season, as well as juvenile growth, both influence the probability of completing sexual maturation at a given age.
For example, low L∞ characterizes a life-history type where individual growth is initially fast (high value of k) but, after early maturation at a small size, the rate of growth levels off.
Diversity in their function has been reported in which LC3B seems to be mostly involved in the elongation of the phagophore membrane, whereas GATE-16 is more important for autophagosome maturation at a later stage.
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10.7554/eLife.03311.005 Figure 2. Absence of epsin stalls endocytic clathrin-coated pit maturation at an early stage.
The block of human Ad replication in murine cells may be related to the low infectivity [ 63], unstable and reduced DNA synthesis [ 59, 61, 64], abortive expression of late proteins, or the defective assembly and maturation at an later stage of viral replication cycle [ 59, 60, 62].
Despite the similar age at maturation, small-selected fish matured at a smaller size (L) than random and large-selected fish (Fig. 2A, Table 1).
The term "organoblast" was used in 1997 in reference to pediatric salivary gland tumors that had morphological characteristics of the organ with maturation arrested at a primitive state of development.
The work was based on the hypothesis that pubertal maturation at baseline is a risk factor for later development of back pain.
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