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Given that Wnt/TCF-4 plays a major role in Paneth cell maturation, aside from its direct function in the expression of Paneth cell α-defensins [31], [32], the observed link between ileal CD and TCF-4 suggests that impaired cell differentiation might be involved in the disorder.
Similar(57)
Aside from premature centrosome maturation, RNAi-mediated depletion of KCA-1 did not result in any noticeable centrosome defects, and duplication proceeded normally.
Thereafter, the piles were moved to the aside place for post-maturation during the phase II.
Aside from anatomic location and cell surface markers, DCs can be further classified based on maturation status.
"It's maturation.
We don't want maturation.
Her slow maturation was not unusual.
Like aging, tennis maturation is subtle.
Temperature also affects sexual maturation.
"Step aside!
The maturation process is a very long one, and intellectual maturation in particular is never ending.
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