Sentence examples for maturation arrest in from inspiring English sources

Thus, we decided to investigate the possibility of a phagosomal maturation arrest in an early stage.

Low or absent expression of HSFY in spermatogenic cells could lead to maturation arrest in men [ 18], and the deletion of HSFY on the human Y chromosome was associated with the unexplained cases of idiopathic male infertility [ 20].

We have demonstrated that espL is required for dissemination to macrophages, which is in line with a very recently published paper demonstrating that phagosomal maturation arrest in macrophages is affected in an M. tuberculosis espL mutant (Brodin et al., 2010).

Our results are in agreement with the study by Appelmelk et al (Appelmelk et al, 2008), who did not detect a defect in phagosome maturation arrest in their ManLAM capping-deficient strains.

In the few cases with a more severe clinical course there may be maturation arrest in the myelocyte/metamyelocyte stage or bone marrow hypocellularity, probably because the autoantibodies recognize antigens expressed not only by mature neutrophils but also by their bone marrow precursors.

18 In addition to T-cell maturation arrest, mutations in the Artemis gene result in B-cell differentiation arrest at the pre-B-cell-receptor checkpoint.

Weedin et al. reported motile sperm in 5 of a total of 44 SCO patients, whereas motile sperm were detected in 30 of 55 HS and 24 of 57 maturation arrest patients in their meta-analysis [ 13].

Photomicrographs also showed that P. tuber-regium prevented the edema, spermatogenic distortions and maturation arrest observed in the CCl4 only group.

Here we describe a zebrafish mutant, frascati (frs)5, that shows profound hypochromic anaemia and erythroid maturation arrest owing to defects in mitochondrial iron uptake.

Transient bi- or multiphenotypic stem cell stages that are preserved as a relic in leukaemic blast populations due to the primary oncogenic event that is involved in maturation arrest (Greaves et al, 1986).

Increased expression of MCM RLFs in response to arrested differentiation (maturation arrest) has also been observed in other tumour types (Williams et al, 1998; Going et al, 2002; Stoeber et al, 2002) and is currently being assessed as a cancer screening tool in multi-centre trials (National Cancer Research Network Trial ID 1279).