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To identify gene programs associated with their in vivo capabilities and limitations, we extended previous gene expression profile analyses to now compare engineered skin after in vivo grafting with both in vitro maturation and normal human skin.
Thus, their increased expression suggests potential roles in OL maturation and normal oligodendritic development.
Treatment of immature fruit with an inhibitor of methyltransferases resulted in ripening of immature fruits well in advance of seed maturation and normal ripening.
We show that autocrine androgen action within developing adult Leydig cells is dispensable for the attainment of final Leydig cell numbers in adulthood but is essential for correct Leydig cell maturation and normal steroidogenic enzyme transcription.
We produced a KO mouse for Rnase10 (12) and report here that the encoded product is the first single epididymal secreted protein found to be essential for sperm maturation and normal male fertility, providing evidence that inactivation of function of a single epididymis-specific gene product may be a feasible strategy to develop a male contraceptive.
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These results further suggest that cPLA2α and its cleaved arachidonic acids play important roles in cortical neuronal maturation and in normal neurochemical processes.
Our positive genetic correlations between growth rate and normal sexual maturation (0.34-0.39) are higher than the estimates reported by Gjerde et al. [ 18] but of the same magnitude as the estimates between growth and early sexual maturity reported by Gjerde and Gjedrem [ 23].
The results provide in vivo evidence for a significant role of the golli proteins in the regulation and maturation of OLs and normal myelination.
The results provide in vivo evidence for a significant role of the golli proteins in the regulation of maturation of OLs and normal myelination.
Based on this, individuals were classified in three groups: early sexual maturation (below first tertile of age), late sexual maturation (second tertile or more) and normal sexual maturation or reference group (between the first and the second tertile) [ 23].
To generate the different gene sets, we used flow-sorting to isolate eight subpopulations of hematopoietic cells of different lineage and maturation from normal donors and established their gene expression patterns.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com