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Surprisingly, this network is also essential for cytoskeletal organisation and its disruption has dramatic effects on nuclear migration, centrosomal positioning, focal adhesion maturation and cell motility.
We next used cell surface biotinylation to test whether the tetracysteine DATs exhibited maturation and cell surface expression comparable to wildtype DAT.
They range from stimulation of proliferation to maturation and cell death.
These responses indicate the induction of maturation and cell death-associated signals in the transgenics, in addition to defense responses.
These results suggest that RB/E2F3 pathway mediates SC maturation and cell cycle quiescence as well as survival.
Furthermore, downregulation of Tln2 and Lrp1b is known to reduce β1-integrin maturation and cell adhesion (Albiges-Rizo et al, 1995; Salicioni et al, 2004).
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Additional studies detecting low levels of uncleaved Notch at the cell surface [29], [30] reinforce our conclusion that S1 cleavage is normally a marker of, rather than a prerequisite for, mammalian Notch receptor maturation and cell-surface delivery.
The overrepresentation of "cell morphogenesis", "cell death", "developmental maturation", and "cell-cell signaling", indicates that the shared gene sets are more likely to have implications for brain cell development and degradation, and neuron-to-neuron or glia-to-neuron interaction, respectively.
They all induce mouse dendritic cell maturation and B cell proliferation.
IL-6 is a driver of B-cell maturation and plasma cell differentiation 13; therefore, clinicians need to understand the impact of IL-6 blockade on immune response.
PC-bearing antigens are able to interfere with key proliferative pathways in B and T cells, DC maturation, and mast cell degranulation [ 120].
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development and cell
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