IL-4 stimulates B cells and also activates DCs and enhances Th2 cell maturation and activation.
Sugawara, K. et al. Endocannabinoids limit excessive mast cell maturation and activation in human skin.
Vogel, D. Y. et al. Human macrophage polarization in vitro: maturation and activation methods compared.
Extended Data Fig. 3 local XRT of the tumor induces maturation and activation of TLR3+ dendritic cells.
We next examined lysosomal acidification, a critical factor for lysosome maturation and activation of most lysosomal enzymes.
Analyses of the resulting hybrid structure of the HsTPPII holocomplex provide new insights into the mechanism of maturation and activation.
TLR-4 is a pattern recognition receptor that senses lipopolysaccharides (LPS) on gram-negative bacteria and initiates pro-inflammatory cytokine induction, maturation and activation in macrophages, dendritic cells and other immune cells.
Similar to oral pathogens, oral commensals can induce maturation and activation of monocyte-derived human DCs.55 Thus, it is likely that additional mechanisms other than just a direct recognition of pathogen-specific molecules might be involved.
The MAPK cascade is involved in numerous male reproductive processes, including spermatogenesis, sperm maturation and activation, capacitation and acrosome reaction, before fertilization of the oocyte.
Methionyl aminopeptidases (MetAPs) are metallo-dependent proteases responsible for removing of N-terminal methionine residue of peptides and proteins during protein maturation and activation.
The immunoregulatory potential of DC1 and DC2 depends on their state of maturation and activation, which can be mediated by several molecules.
