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Here the problem seems to be a matter of dose.
The apparent slow onset of naratriptan 2.5 mg is, however, a matter of dose (see above).
Therefore, the difference is probably simply a matter of dose rather than choice of 'buffer'buffer
It is possible that this is a matter of dose, or that the DNA damage inflicted by IR overrides the blunted oxidative stress in the SVZ.
In regard to global DNA methylation changes most likely is just a matter of dose as we have in vitro evidence that hydralazine produces global DNA hypomethylation in MCF-7 cells as evaluated by the same methods here used.
This may again be a matter of dose, as the amount of RA used in our experiment (0.64 μg/mL) was lower than that reported bioactive by others (1.0 μg/mL) [ 24].
Similar(53)
Treatment with VPA will not be matter of dose-finding but a titration strategy will be applied in each patient looking for a serum concentration that is considered useful to produce the desired synergistic effect with radiotherapy and/or chemotherapy.
But autoimmunity is more than a simple matter of estrogen dosing.
Treating children is not just a matter of smaller doses, adds pediatrician Harvey Cohen of Packard Children's Hospital in Stanford, California; for example, one leukemia drug that was safe for adults has been found to pose dangers for a child's developing heart.
These conflicting results could be a matter of cumulative-dose exposure secondary to long-term treatment (μM, not nM level) and should be investigated.
It is still a matter of debate which dose of vitamin D3 (or potentially D2) supplementation is necessary/optimal, taking into account baseline vitamin D status and the desired serum levels to be achieved by supplementation [ 31- 33].
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