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Exact(6)

Nevertheless, the contribution of white matter damage to impairment following cortical lesions cannot be discounted.

Our findings suggest that future treatment strategies should target both white and gray matter damage to prevent the neurologic deficits in survivors of prematurity.

Similar evidence for plasticity has also been demonstrated in the visual system where diffusion tractography imaging clearly identifies thalamo-cortical axon circumnavigation of white matter damage, to reach their predetermined destination in the occipital cortex [ 21].

Two different TBI models were used that produced either primarily gray matter or primarily white matter damage to determine whether the response to injury was specific to the site or cell type damaged.

It has been suggested that the increased prevalence of apathy and depression in SVD may be caused by white matter damage to the cortico-subcortical pathways that connect brain regions important for regulating emotion (Taylor et al., 2013).

While neuropathological studies have shown that the frontal lobes appear to be the most severely affected by white matter abnormalities [ 23], we have found using structural MRI that frank white matter damage to more posterior areas is associated with incident AD [ 9, 35].

Similar(54)

Eight days later, Pulvertaft phoned the publisher and said he understood Parker, an "informed author", may have included matters damaging to national interests.

Also, at the other end of the lifespan, white matter damage due to axonal loss that occurs in normal ageing has been found to correlate with working memory performance, even after controlling for age [ 19].

Further analysis revealed that minocycline attenuated long-term white matter damage adjacent to the striatal injury core, which correlated with sustained functional benefits.

These data confirm the protective effects of taurine against gray and white matter damage due to CHI, and suggest that down-regulating calpain activation could be one of the protective mechanisms of taurine against CHI.

This more protracted time course of white matter damage, compared to grey matter, suggests that white matter should be a key target for initial therapeutic treatments and that there is a window of opportunity of several days during which agents could be administered to help support white matter survival.

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