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Age-related grey matter changes were investigated by comparing young and older adults using voxel-based morphometry and voxel-based cortical thickness methods.
The grey matter changes were modulated additionally by the presence of co-morbidities and symptom severity.
Gray matter changes were observed within the cerebellum as well but were less pronounced.
Associations of the MetS with fronto-subcortical syndrome and with frontal white matter changes were found by others [ 10, 40].
Frequently the white matter changes were related to previous conditions/insults and included infection, ischaemia, hypoxia, and prematurity.
The spectrum of findings is presented in table 2. Common findings besides white matter changes were tumours, atrophy, infarctions and sinusitis.
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Corn, B. W. et al. White matter changes are correlated significantly with radiation dose.
For MD, we again found that the growth trajectories were best fit by the un-shifted time courses, suggesting that white matter changes are coupled to reading experience and, therefore, track improvements in Reading Skill.
Although white matter changes are part of the small vessel disease spectrum, they are discussed separately above.
Second, to analyze if white matter changes are present in the aforementioned areas in individuals with higher cognitive reserve that would result advantageous in terms of migraine chronification.
However, white matter changes are emerging as seen in Patients 1 and 3 which included abnormal periventricular white matter changes with subtle signal abnormalities in the basal ganglia and minimal, symmetric signal abnormalities involving the deep frontoparietal cerebral white matter, respectively.
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