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The short reinforcing elements lead to an effective crack bridging of the fragile matrix, which contributes to the improvement of the mechanical performance of the composite after ageing.
CAFs secrete tumor promoting effectors such as SDF-1, HGF, and TGF-β into the tumor microenvironment, and they overproduce extracellular matrix, which contributes to tumor rigidity and an altered signaling context thus further promoting tumor progression [5], [11], [12].
On activation, HSCs differentiate into myofibroblasts, representing the major producers of extracellular matrix, which contributes to fibrosis.
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This aggregation resulted to the uneven dispersion of multi-walled carbon nanotubes (MWNTs) in the matrix, which contributed to the lower value of the strain-at-break of the films (Xiong et al. 2006).
Furthermore, the theoretical simulation from Young's modulus of the composite films indicated that the GO nanosheets had unidirectional arrangement tendency rather than random dispersion in cellulose matrix, which contributed to the improvement in the elongation of the composites, which was supported by the SEM results of the cross-section of the broken composite.
The myofibroblast has been associated with the expression of several matrix proteins which contribute to matrix deposition [ 46].
These populations, called biofilms, are encased in a matrix of exopolysaccharides, which contributes to the mechanical and biological properties of the community.
TNF-α induces synovial fibroblasts to express cytokines (such as IL-6) and other factors such as, e.g., matrix metalloproteinases, which contribute to cartilage and bone destruction.
57 They cause altered expression and function of RyR2 via post-translational modifications of extracellular matrix components, which contribute to systolic and diastolic dysfunction.
It is the combination of all of these that leads to particular microstructure types, each of which contributes to matrix permeability differently.
Leptin has also been shown to stimulate synthesis of type I collagen in mesangial cells and type IV collagen in glomerular endothelial cells which contributes to extracellular matrix deposition, glomerulosclerosis, and proteinuria [16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com