It was confirmed that crazing, microcracks formation and debonding of nanoparticles from the matrix were the main causes leading to the improvement of fracture toughness.
Optical microscopy showed that the small size of the HA-CS granules (10 μm) and good dispersion of the granules in the PCL matrix were the reasons for the good mechanical properties compared with the other blends.
Model analysis demonstrated that both the gradual restoration of BM and degradation of latent TGF-β1 in the matrix were the main mechanisms.
A term-by-gene matrix was created for mouse and human genes where the entries of the matrix were the weighted frequencies of terms across the entire collection.
The genes annotated in the inner membrane and matrix were the most negatively correlating gene sets within mitochondria.
Based on these results, we established that the most suitable hADSCs for incorporation into the alginate matrix were the cells corresponding to the third cell passage.
