Sentence examples for matrix to stimulate from inspiring English sources

Our expectation is that the Global Research in Paediatric (GRiP 3), implementing an infrastructure matrix to stimulate and facilitate the development and safe use of medicines in children will provide a fundamental contribution in both these fields.

Mature osteoclasts secrete factors such as cardiotrophin-1, Wnt 10b, BMP-6, sphingosine-1-phosphate, and semaphorin D. 7– 9 When osteoclasts resorb bone, factors such as transforming growth factor beta, insulin-like growth factors 1 and 2, and bone morphogenetic proteins are released from bone matrix to stimulate osteoblast proliferation, differentiation and/or activity.

Furthermore, acellular-derived matrices serve to stimulate proliferation and recruitment of endothelial cells by providing proliferation signals to cells.

Plasma FN is then deposited and crosslinked to the provisional FN-rich matrix, and functions to stimulate platelet adhesion and aggregation, and fibroblast spreading and invasion into the clot.

Transforming growth factor (TGF β is known to stimulate matrix formation in cartilage, and ADAMTS-4 production in synoviocytes.

Thus, laminaran can be used to increase the rate of production of reconstructed self-assembled dermis and can also potentially be used in cosmetic or therapeutic creams to stimulate matrix production.

The ability to stimulate matrix production without inducing high active tension will aid in the development of robust tissue engineered heart valves and other connective tissue replacements where minimizing tissue shrinkage upon implantation is critical.

For example, the dynamic compression of cartilage explants by approximately 3% was shown to stimulate matrix synthesis while graded levels of static compression did not [49].

These results suggest that peptide scaffold functionalization with cell adhesion motifs which interact with integrin may be useful to stimulate matrix protein production from fibroblasts.

The protective effect on cartilage and bone destruction might be explained in part by the fact that CCL2/MCP-1 is able to stimulate matrix metalloprotease-3 [ 23].

On the other hand, an increase in intracellular cAMP concentration was without any effect on proliferation [ 21], but was able to stimulate matrix synthesis [ 22].