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Osteoprogenitor cells in turn give rise to and maintain the osteoblasts that synthesize new bone matrix on bone forming surfaces, the osteocytes within bone matrix that support bone structure, and the protective lining cells that cover the surface of quiescent bone.
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The stroma is the supportive framework of biologic tissue consisting of an extensive extracellular matrix that supports cells, separates tissues and regulates intercellular communication.
Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that supports the development of adipose stroma within a robust freely permeable matrix.
A network of proteins and polysaccharides function together in the extracellular matrix that supports the cells of the body, including the nervous system.
In the perisinusoidal space are hepatic stellate cells, which store retinoids and produce extracellular matrix that supports the liver's architecture.
For the production of clinical-grade human iPSCs, the matrigel can most likely be replaced with defined matrix that supports both donor cell and iPSC growth, such as vitronectin [32].
Wound dressings that contain collagen products create a biological scaffold matrix that supports the regulation of extracellular components and promotes wound healing.
The otolithic membrane is equivalent to the mammalian otoconial membrane, a gelatinous matrix that supports the otoconia above the utricular and saccular epithelium in the mammalian ear.
Best known as a component of blood plasma that is essential for blood clotting, fibrinogen is also found in the extracellular matrix that supports cells, and on the surface of inflamed cells.
In contrast, an injectable polyHIPE that cures within 15 min would be advantageous because it can stabilize the defect and be loaded with cells prior to injection to provide a temporary matrix that supports tissue regeneration.
Cost-effective and scalable synthetic matrices that support long-term expansion of human pluripotent stem cells (hPSCs) have many applications, ranging from drug screening platforms to regenerative medicine.
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