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The penetration of parylene into PDMS matrix that occurs during deposition was measured using time-of-flight secondary ion mass spectrometry (TOF-SIMS).
The latter group included gene expression clusters that correspond to the degradation and remodeling of the extracellular matrix that occurs during the second phase of mammary gland involution.
This suggests that DESC1 could participate in the degradation of the extracellular matrix that occurs in normal and pathological conditions, including cancer.
In the literature reported previously, renal fibrosis is the consequence of the activation and accumulation of fibroblasts, and the deposition of abundant ECM (extracellular matrix) that occurs in virtually every type of the CKD [ 4].
In our case, the lesion's clinical appearance was typical of an eyelid pilomatixoma, a benign tumor originating from the hair follicle matrix that occurs frequently in the sub-brow area in the pediatric age group.
The loss of cartilage matrix that occurs in osteoarthritis (OA) is associated with a disturbance in the balance of anabolic (synthetic) and catabolic (destructive) activities of the articular chondrocytes [ 1].
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These experiments only reveal the recoverable, elastic component of the cell-applied strains and not any permanent rearrangements due to mechanical creep or chemical modifications of the matrix that occur during the prolonged application of force.
Roles for Rho GTPases are complicated by cell spreading and integrin-based adhesions to the extracellular matrix that occur concurrently with cell-cell adhesion, and which also require Rho GTPases.
MMPs therefore contribute to the tissue resorption and remodeling of the extracellular matrix that occur in reaction to tissue degeneration [ 6].
Other regulatory mechanisms include variations in pH of the extracellular matrix that occur during growth arrest [ 45], physical contact between enzymes and their substrates [ 10] and proteolytic degradation.
Changes in the composition and morphology of the extracellular matrix that occur during heart development and heart disease affect the activity of cardiomyocytes.
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