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The percentage of drug released from guar gum matrix tablets reduced in the physiological environment of stomach and small intestine.
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The results showed that ethylcellulose coating of HCTZ matrix tablets is effective in reducing the variability of drug release from the tablets.
It can be seen that incorporation of EC in guar matrix tablets F16, F17, and F18 resulted in reducing the drug release rate from guar matrix tablet F6.
Matrix tablets were made by direct compression method.
Matrix tablets were prepared by the wet granulation technique.
The novel 5-FU matrix tablet fulfills therapeutic needs by engineering matrix tablets utilizing chitosan sodium alginate interpolyelectrolyte complex (IPEC).
The study showed that an equation based on percolation theory can adequately model tablet strength density profiles from matrix tablets.
The increased amount of shellac and increased annealing temperature significantly affected the physical properties (i.e., tablet hardness and tablet disintegration) and MZ release from the matrix tablets.
Two types of extended-release tablets (simple matrix tablets and press-coated tablets) were prepared and their potential as extended-release dosage forms were assessed.
In the vivo study, the MRT was prolonged for matrix tablets when compared with commercial immediate release tablets.
Simple matrix tablets have a large amount of hydroxypropylcellulose as a rate-controlling polymer and the matrix is homogeneous throughout the tablet.
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