Sentence examples for matrix synthesis in from inspiring English sources

Dex was required for optimal matrix synthesis in both hydrogels, but was found to decrease cell viability in agarose constructs.

Fibrosis severity was substantially decreased after UUO with a corresponding decrease in matrix synthesis in macrophage CD36-deficient mice.

Scaffolds fabricated from cartilage extracellular matrix provide a chondroinductive environment that stimulates cartilaginous matrix synthesis in a variety of cell types.

Osteogenic Protein 1 (OP1/BMP7) was evaluated for the ability to enhance extracellular matrix synthesis in healthy and OA meniscus cells.

Objective: Various strategies have been tested to direct and control matrix synthesis in tissue engineered cartilage, including mechanical stimulation of the construct both before and after implantation.

Notably, application of the sox9 vector increased the levels of matrix synthesis in the aspirates in both systems at any time point examined compared with the control treatments (up to 8- and 14-fold difference for safranin O and type-II collagen, respectively, P ≤ 0.001).

Overall, these multifaceted effects by changes in ECM, including dysregulation of matrix synthesis (reduction in collagen type II and aggrecan, increase in collagen type I and X), upregulation of matrix degradation, and induction of cell apoptosis, promote the progression of OA by altering the cellular behaviors of chondrocytes.

A variety of growth factor cDNAs enhance matrix synthesis after in vivo, virally mediated gene transfer to the discs of rabbits [ 40].

Interestingly, AGEs may bind to their cell surface receptor, RAGE, initiating a cascade of signals influencing cell cycle and proliferation, gene expression, inflammation and extracellular matrix synthesis (reviewed in Bierhaus et al).

Amino acids are essential to organic matrix synthesis, which in turn is vital to coral calcification (Allemand et al., 1998; Ferrier-Pagès et al., 2003; Houlbrèque et al., 2004b).

Degeneration of the intervertebral disc (IVD) is characterized by increased extracellular matrix breakdown, abnormal (fibrotic) matrix synthesis, inflammation, and in-growth of nociceptive nerves and blood vessels into a typically aneural and avascular tissue.