Scanning electron microscopy evaluation showed cell proliferation throughout the fibrin matrix, suggesting the possible application of human fibrin as the bioengineered tissue scaffold at non-load-bearing sites.
Cavities smaller than 2 μm are basically nearly spherical in shape and randomly dispersed in the matrix, suggesting the involvement of diffusion or superplasticity diffusion controlled cavity growth mechanism.
However, these recruited blood vessels and osteoclasts did not invade the hypertrophic cartilage matrix, suggesting the inability of the cartilage matrix itself to become invaded.
Present interpretations, based on recent experiments with lathyritic rat bone matrix, suggests the morphogenetic property emanates from nonsolubilized components [ 9].
Furthermore, we found that non-invasive MEF cells failed to invade both in the presence or absence of mechanical stimulation into collagen/fibronectin matrices, suggesting the need for a cell to have a pre-defined ability for invasion.
The spectral fluorescence excitation-emission matrices suggested the presence of mixtures of PAH-DNA adducts in some of the eluates.
Thus, data obtained from glutaraldehyde cross-linked matrix, like data obtained from dinitrophenylated matrix, suggest that the bone morphogenetic activity depends on the undenatured native protein structure.
Estimates of the increase in toughness associated with the compressive residual stresses in the matrix suggest that this mechanism makes a significant contribution to the toughening effect of the Al2O3 platelets.
Furthermore, within the range of experimental temperatures, the activation energy of the reorientational relaxation rates of HNMA is close to that of the γ-process of the PMMA matrix, suggesting that the relaxation of the anthracene moieties is affected by the rotational motions of the α-methyl groups on the PMMA chain backbone.
These increases in buffer α-KG in the absence of a reduction in the matrix suggest that net production of α-KG occurred during the 20 min incubation.
