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(21) In the context of adhesive hydrogel use for tissue repair and reconstruction, it is appropriate to introduce susceptibility to extracellular matrix proteases involved in matrix restructuring and wound healing processes.
While many of these genes are considered 'repair' genes involved in matrix restructuring and tissue repair, as well as the down-regulation of the classical inflammatory response, their effects may not be fully beneficial.
Based on the current knowledge of the function of the corresponding proteins, the brain's immune phenotype found in the APPSw mice is more likely to be associated with matrix restructuring and down-regulation of classical inflammatory signalling rather than toxicity (Gordon, 2003; Colton, 2009).
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Thus, a block in CD11b/CD18-mediated CD11b/CD18-mediatedadherenceandnces can regulatoryaddimbalancescandaresultects after TPA stinuladditionalh asecondaryleffectslafter of proliferaTPAn and a failed extracellular matrix restimulation by the lack of a suchicient production of masrix metalloproteinases.
Based on data obtained in our study, we can conclude that MMP-2 and TIMP-1 levels in patients with chronic heart failure are not exclusively markers of cardiac matrix restructuring.
Increase of both TIMP1 and MMP1 expression, and thus exertion of both fibrotic and matrix-degrading effects, could be seen in the light of a necessity to establish a balance between matrix deposition and restructuring during the process of fibrogenesis.
Functional analysis revealed a prominent presence of genes encoding proteases and protease inhibitors, cell adhesion molecules, extracellular matrix elements and cytoskeletal molecules potentially related to tubular restructuring and changes in cell junction dynamics.
All have been restructuring and delaying or canceling new projects.
"Restructuring and upgrading is in an uphill stage.
"The banks are restructuring and they're recovering.
Hence, classifications are made according to "portfolio restructuring," "financial restructuring," and "operational restructuring" (Eichner 2010).
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