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Let M′ denote the matrix restored by substituting the modified eigenvalues into S such that M ′ = c 1 ′ c 2 ′ c 3 ′ c 4 ′ ⋯ ⋯ c N / 2 − 1 ′ c N / 2 ′ = U λ 1 ′ 0 0 λ 2 ′ 0 0 ⋯ ⋯ 0 0 V T. (20).
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Some of the extracellular matrix and membrane components that were upregulated in SAMP8 were restored by CR (i.e., proteinaceous matrix, collagen, basement membrane) (see Table S4, Supporting information).
Other gene sets upregulated in SAMP8 but restored by CR were associated with organogenesis processes, extracellular matrix organization and MAPKKK cascade signaling (Table S3, Supporting information).
When both the LE and perichondrium are disrupted, matrix metalloproteinase (MMP) levels within adjacent chondrocytes are diminished but can be restored by exogenous TGF-β3.
Many of these crucial microenvironmental cues may be restored by generating three-dimensional (3D) cultures that use laminin-rich extracellular matrix (commercial Matrigel).
This was a cell autonomous function of Akt1 since the impaired differentiation and matrix synthesis shown by ALP and Alizarin red stainings in the Akt1-/ osteoblast culture were restored by introduction of Akt1CA (Fig 4C).
Utilities were restored by Monday evening.
The observatory was extensively restored by 1993.
Beautifully restored by Kevin Brownlow and Patrick Stanbury.
Service was restored by evening.
Service was fully restored by 4 p.m.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com