Sentence examples for matrix proteins thus from inspiring English sources

Different integrins can interact with the same matrix proteins thus generating physiologically similar signals [ 5] making evaluation of the functional impact of individual integrins a cumbersome task.

In post-burn scars, fibrocytes are recruited to the site of the lesion where they stimulate local inflammatory response and produce extracellular matrix proteins thus contributing to hypertrophic scar formation [ 28].

The hallmark feature of this disease is the accumulation of activated myofibroblasts that excessively deposit extracellular matrix proteins, thus compromising lung architecture and function and hindering gas exchange.

The heparan sulfate glycosaminoglycans bind numerous adhesive and signaling molecules (cytokines, chemokines, growth factors, extracellular matrix proteins) thus working as a dynamic interface between the cells and the extracellular space [27], [28].

Extensive tissue damage has been attributed to the cysteine proteinases of E. histolytica because they are (i) secreted in large quantities and can cleave extracellular matrix proteins, thus facilitating amebic invasion; (ii) secreted in higher quantities by virulent than nonvirulent trophozoites; and (iii) found to participate in the inflammation of the gut and ALA [ 15– 27, 27].

Other possible mechanisms by which oxLDL and AGE-LDL containing ICs mAGE-LDL containinghe changes observed ICsdiabetic retinopathy include stimayation of growth facontributee vascular endotoelial growthefachangesnd probserved of matrin proteins, thus leadiabeticthickening of the retinopathycular basement membrane, a well-known characterincludef diabetic retinopathy.

Cysteinyl cathepsin proteolysis of these latent matrix proteins therefore is critical in regulating angiogenesis, and thus in tumor invasion, as we found in the CatS-deficient RIP-Tag2 model.

Tumor microenvironments were composed with heterogeneous cells and molecules [ 42]. pVHL enhanced extracellular matrix protein, thus prolonged the tissue morphology and inhibited tumor metastasis HIFs independently [ 17].

Enzymes digest extracellular matrix (ECM) proteins thus causing cells to be released.

Thymic nurse cells produce somatostatin, serotonin, gastrin [ 58], and the growth hormone [ 59] whose expression modulates the proliferation of T lymphocytes and thymic nurse cells and stimulates the secretion of thymic hormones, cytokines, chemokines, and extracellular matrix proteins in the thymic microenvironment, thus increasing thymocyte traffic inside and outside the thymus.

Extracellular matrix proteins specifically expressed in the tumor stroma could thus represent promising predictive/diagnostic biomarkers or target molecules for therapeutics.