Sentence examples for matrix protein import from inspiring English sources

Indeed, Pex4 plays an important role in matrix protein import (Wiebel and Kunau 1992), whereas Ubc4 is not required for this process.

Mutations in genes that cause faulty peroxisome function, particularly those that affect matrix protein import, result in a variety of severe inherited human diseases referred to as peroxisome biogenesis disorders.

The inner mitochondrial membrane contains proteins with five types of functions: Those that perform the redox reactions of oxidative phosphorylation ATP synthase, which generates ATP in the matrix Specific transport proteins that regulate metabolite passage into and out of the matrix Protein import machinery.

TRIP8b belongs to the tetratricopeptide domain proteins with homology to the peroxisomal targeting signal 1 (PTS1) receptor protein Pex5p known to be involved in peroxisomal matrix protein import [58] [60].

The actual mode of matrix protein import is still elusive.

The final step in PTS1 matrix protein import is the recycling of Pex5 to the cytosol.

All matrix proteins imported into the mitochondrion from the cytoplasm must pass through the outer and inner membrane and therefore also through the intermembrane space.

The difference of potential between the mitochondrial intermembrane and matrix also contributes to protein import of preproteins.

Hsp70 is another matrix localised chaperone involved in protein import, folding and complex assembly but also has a significant role in iron sulphur cluster formation [52,53].

These findings are similar to those reported for the PEX13-null animals (Maxwell et al., 2003), and are consistent with the established function of PEX13 in peroxisomal matrix, but not in membrane, protein import (Gould et al., 1996; Liu et al., 1999).

The major mitochondrial heat shock protein 70 (mthas70) has a dual role in driving ATP-dependent protein import into the matrix and assisting in folding of proteins.