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It is therefore not a problem if matrix particles are measured, since their spectra can easily be recognized and sorted out.
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As a consequence, the pore volume inside the wax matrix particles is increased and the diffusion coefficient of the drug is altered.
Wax matrix particles were prepared by using acetaminophen (APAP), a model drug; glyceryl monostearate (GM), a wax base; and aminoalkyl methacrylate copolymer E (AMCE), a functional polymer that dissolves below pH 5.0 and swells over pH 5.0.
A three-factor, three-level (33) Box Behnken design was used to evaluate the effects of several of the variables in the model formulation, and the release of APAP from wax matrix particles was evaluated by the paddle method at pH 4.0 and pH 6.5.
Undissolved matrix particles were removed by centrifugation.
Finally, the matrix and particles are meshed with solid elements for further numerical analysis.
The novel adjuvant Gram-positive enhancer matrix (GEM) particles are produced from the food-grade bacterium Lactococcus lactis (29).
Demineralized bone matrix (DBM) particles are obtained from human cortical bone and vary between 1 and 3 mm in size.
Thin composite films consisting of a matrix with embedded particles are currently being developed both as hard, wear resistant coatings and as functional surfaces.
Decoupling of these two types of energy dissipation is important in order to design the particle size and the weight ratio of particles to the matrix that the particles are filled in the particle-filled polymeric composite materials.
The filler particles present in a polishing instrument must have higher hardness than the filler particles of the composite resin so that the resin matrix and the particles are both reduced to a higher surface smoothness [21, 23].
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