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Bone is composed of an organic phase that contains (i) bone forming cells (osteoblasts and osteocytes), (ii) bone resorbing cells (osteoclasts) and (iii) a matrix of collagen and non-collagenous proteins (osteoid), and a mineral phase of inorganic salts.
To her surprise, she found that it still contained a matrix of collagen fibres, a protein that gives bone its structure and flexibility.
The second layer, the dermis, is thicker and is composed of loosely packed connective tissue cells in a watery matrix of collagen and elastin fibres, as well as sweat glands, hair follicles, capillaries, and lymphatic vessels.
Cartilage is an intricate balance of water, chondrocytes, and a rich extracellular matrix of collagen fibers and proteoglycan molecules.
Parchment artefacts can therefore be described structurally, as a matrix of collagen fibres interfaced with a gelatine exterior.
These mesothelial cells rest on a matrix of collagen, elastic fibres, blood vessels and lymphatics, allowing the lung and chest to expand and contract [1].
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Proteoglycans (PGs) are multifunctional biomacromolecules of the extracellular matrix of collagen-based tissues.
In this model, human lung epithelial type II pneumocytes and human primary macrophages/monocytes were seeded into a matrix of collagen-embedded fibroblasts.
The uninfected lung tissue model was recently established (by two of the co-authors) using human primary macrophages and monocytes together with cell lines of lung epithelial pneumocytes and fibroblasts, which were cultured on a matrix of collagen-embedded fibroblasts.
Adult articular cartilage is an avascular tissue composed of a specialized matrix of collagens, proteoglycans, and non-collagen proteins, in which chondrocytes constitute the unique cellular component.
As a control, they did something similar using matrices of collagen (a protein abundant in bone) instead of ersatz marrow.
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