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(V2) VIABLE High confidence for viable mutations (novel codon predictions) is assigned based on codons observed in the expanded library (eg, DENV-1234 codon frequency matrix; Observation O4).
The currently proposed seven levels of confidence scores (viable: V1 V4, non-viable: N5 N7) that are assigned to predictions and assessment of possible sequence changes are as follows: (V1) VIABLE Highest confidence for viable mutations is assigned based on codons observed in the reference library (eg, DENV-2 codon frequency matrix; Observation O0).
Transmission matrix, observation matrix, and pattern are also needed.
Transmission matrix, observation matrix, and pattern are also mined.
This investigation utilizes a matrix observation method to analyze triple helices.
Based on the theoretical research, a matrix observation method of a triple helix is invented.
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Additionally, matrix observations are non-independent, based upon paired datapoints.
Mantel test results, reported below, overcome the non-independence of matrix observations, and allowed us to accurately assess the relationship between geography and molecular evolution.
ANOVA can, in some cases, be a problematic test for non-independent matrix observations, but the inclusion of the region variable helps to overcome spatial dependence in the dataset.
The rows of the matrix (observations) represent the targets, and the columns (attributes) represent the trans-factors.
After peak annotation, the obtained data matrix (observations: biological replicates, variables: 171 annotated peaks) was used for statistical analyses including multivariate analysis and correlation analysis as log10-transformed data.
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